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2003 U.S. Open Seeds
Men
| Seed | Player | Status |
| 1 | Andre Agassi, United States | |
| 2 | Roger Federer, Switzerland | |
| 3 | Juan Carlos Ferrero, Spain | Advanced to second round |
| 4 | Andy Roddick, United States | |
| 5 | Guillermo Coria, Argentina | |
| 6 | Lleyton Hewitt, Australia | |
| 7 | Carlos Moya, Spain | |
| 8 | Rainer Schuettler, Germany | |
| 9 | Sebastien Grosjean, France | OUT - first round (Delgado) |
| 10 | Jiri Novak, Czech Republic | |
| 11 | Paradorn Srichaphan, Thailand | |
| 12 | Sjeng Schalken, Netherlands | |
| 13 | David Nalbandian, Argentina | |
| 14 | Gustavo Kuerten, Brazil | |
| 15 | Fernando Gonzalez, Chile | |
| 16 | Martin Verkerk, Netherland | |
| 17 | Tommy Robredo, Spain | OUT - first round (Verdasco) |
| 18 | Max Mirnyi, Belarus | |
| 19 | Agustin Calleri, Argentina | |
| 20 | Mark Philippoussis, Australia | |
| 21 | Felix Mantilla, Spain | |
| 22 | Younes El Aynaoui, Morocco | |
| 23 | Wayne Ferreira, South Africa | Advanced to second round |
| 24 | Mardy Fish, United States | Advanced to second round |
| 25 | Albert Costa, Spain | |
| 26 | Marat Safin, Russia | Withdrew (wrist injury) |
| 27 | Mariano Zabaleta, Argentina | |
| 28 | Yevgeny Kafelnikov, Russia | |
| 29 | Feliciano Lopez, Spain | |
| 30 | Gaston Gaudio, Argentina | |
| 31 | Arnaud Clement, France | Advanced to second round |
| 32 | Vincent Spadea, United States | |
| 33 | Juan Ignacio Chela, Argentina |